Research Associate II - Stanley Center for Psychiatric Research

Company Name: Broad Institute of MIT and Harvard
Location: USA

Job Description

The goal of the Stanley Center for Psychiatric Research at the Broad Institute is to improve mental health through research. Over the last several years, the Stanley Center and the psychiatric genetics community have gained unprecedented insight into the genetic basis of epilepsy, autism, schizophrenia and bipolar disorder. Our focus now is to determine how the genetic findings contribute to disease mechanisms, which is essential for the identification of drug targets and eventually the development of effective treatments. The position provides the opportunity to join a new and rapidly expanding team focused on developing adeno-associated viruses (AAV) for efficient and targeted expression in the central nervous system. The successful candidate is expected to explore this possibility using a wide variety of approaches, including AAV engineering for gene delivery and therapy. The candidate should have a strong background in neuroscience, have experience in molecular biology, and computational biology.

Characteristic duties

• Perform molecular cloning of plasmids
• Perform systemic and stereotactically guided injections of viral vectors
• Perform immunohistochemistry analysis and confocal imaging
• Perform next-generation sequencing experiments (scATAC-seq, scRNAseq)
• Analyze large datasets
• Document, compile, and analyze experimental data
• May perform other duties as assigned
  
  

Requirements

• BS/MS in biology, neurobiology, molecular/cellular biology with 2+ years of relevant research experience
• Prior lab experience in designing and performing molecular cloning of plasmids, performing systemic and stereotactic injections, tissue processing and immunohistochemistry, and imaging techniques and microscopy preferred
• Computation skills for analysis of large datasets
• Must be able to work independently and on multidiscipline project teams
• Outstanding personal initiative and communication skills
• Exceptional organizational and time management skills and attention to detail
• Must be willing and able to develop and shift plans in service of a rapidly changing environment
  

The Broad Institute will not offer Visa sponsorship for this opportunity.

EOE / Minorities / Females / Protected Veterans / Disabilities

EEO is The Law - click here for more information

Equal Opportunity Employer Minorities/Women/Protected Veterans/Disabled
Check out this video for a look into our community!

• Seniority level

  Not Applicable

• Employment type

  Full-time

• Job function

  ResearchAnalystInformation Technology

• Industries

  ResearchBiotechnologyHospital & Health Care